Best OTC Weight Loss Substitutes To Ozempic & Saxenda

What is Saxenda?

Liraglutide is a prescription medication included in Saxenda. Liraglutide is related to a hormone that occurs naturally in the body and regulates insulin levels, digestion, and blood sugar levels. Saxenda should be used in conjunction with a low-calorie diet and increased physical exercise. It is used to treat obesity and body weight reduction in adult patients with a BMI of 30 kg/m2 or above, or 27 kg/m2 or higher if you have type 2 form of diabetes, or elevated blood pressure, triglycerides, high cholesterol, or a low level of HDL cholesterol, leading to plaque buildup in your arteries to worsen.

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Saxenda is not intended to treat type 1 or 2 diabetes or to aid in weight reduction. Saxenda is part of a therapy regimen that includes nutrition, exercise, and weight control.

Saxenda is administered as an injection administered subcutaneously under the skin. 

It may be used at any time of day, on an empty stomach or with food. 

Saxenda comes in the form of a prefilled pen. 

You should never pump into the same spot twice in a row. 

Do not use the injection if it contains particles or has changed color. 

Consult a doctor or pharmacist about a new medication. 

Use a puncture-proof sharps disposal container to dispose of spent needles and syringes. 

Unopened pens should be kept in the refrigerator. 

Pens in use may be stored at room temperature. 

Always keep your medications out of the reach of youngsters and dogs.

Brand-name medication Victoza has the same active component as Saxenda. However, it is used to treat type 2 diabetes. The difference lies in the dose.

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Saxenda Active ingredients

Liraglutide is a human GLP-1 receptor agonist that has been acylated. The GLP-1 receptor is bound and activated by liraglutide. Liraglutide has a half-life of 13 hours, which is much longer than the body’s natural GLP-1, with a half-life of up to 2 minutes. Liraglutide is resistant to degradation by enzymes in the body and has a longer half-life. Due to its long half-life (13) and slow absorption (due to plasma protein binding) from a subcutaneous injection, liraglutide may be administered once daily.

GLP-1 is a hormone that regulates hunger and calorie intake. This implies it operates via a technique known as negative responses. The GLP-1 receptor is found in numerous locations of the brain that regulate hunger.


To aid in the management of obesity in adult patients with a BMI of 30 kg/m2 or above, or 27 kg/m2 or greater, if you have type 2 form of diabetes, high blood pressure, or a low HDL cholesterol level or high cholesterol, triglycerides, that is causing plaque buildup in your arteries.

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What are the advantages of Saxenda?

Saxenda has demonstrated that it is a very effective weight reduction supplement. Along with lifestyle modifications like diet and exercise, over 85% of those who take it report losing weight.

A 56-week trial was done in which participants were given Saxenda coupled with a low-calorie diet and an activity program. According to the findings, three out of every five participants dropped more than 5% of their body weight (an average of 5kg), and one out of every three people shed over 10% of their body mass (at an average of 10kg).

Side effects of Saxenda

The following are the most prevalent Saxenda side effects:

●    Nausea

●    Stomach pain

●    Vomiting

●    Constipation

●    Diarrhea

●    Fast heart rate

●    Dizziness

●    Headaches 

●    Tiredness

Saxenda may produce major negative effects in rare cases. These are some examples:

●    Accelerated heart rate

●    Suicidal tendencies 

●    Abrupt shifts in mood and behavior 

●    Uncontrollable vomiting, nausea or diarrhea 

●    Hypoglycemia (extremely low levels of blood sugar) – extreme fatigue, shaking, confusion,fainting, sweating, or convulsions

●    Pain or trouble urinating, ankle or foot swelling, weariness, and difficulty breathing

●    Swallowing difficulties, a lump, or a bloated neck

●    Jaundice – characterized by yellowing of the skin or eyes, darker feces, and upper stomach discomfort that spreads to the back.

Your doctor will weigh the advantages of taking Saxenda against the risks of side effects.

Saxenda warning and precautions

The following categories of people should refrain from using Saxenda. Those who:

●    Are hypersensitive to one or more of the other components of Saxenda.

●    Are taking albiglutide or insulin, exenatide or dulaglutide

●    have Multiple endocrine neoplasia type 2

●    have a record of medullary thyroid cancer in your family

●    Have diabetic ketoacidosis

●    Have not yet reached the age of 18

●    Before beginning treatment with Saxenda, it is important that you discuss the following with your healthcare provider:

●    Are currently using any of the drugs that have the potential to have an interaction with Saxenda

●    Have Kidney disease .

●    Have a disease of the liver

●    Have a high level of cholesterol or triglycerides in your blood.

●    Have issues with your heart

●    Have been having issues with your gallbladder or pancreas

●    Feel depressed or have thoughts of ending your own life.

●    Have stomach or digestive issues

●    Are pregnant or intending to get pregnant Are nursing or intending to start breastfeeding 


Once everyday

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What is Ozempic?

Ozempic is a brand of drug that is made by Novo Nordisk and is prescribed to individuals diagnosed with type 2 form of diabetes for the following reasons:

●    Reduce levels of glucose in the blood when combined with regular exercise and positive dietary modifications.

●    People who already have heart disease should have a lower chance of experiencing serious cardiovascular events such as heart attacks and strokes.

When taken in conjunction with changes in food and lifestyle, Ozempic may be able to assist you in lowering your blood sugar levels. If you have heart disease, it will help the body produce more insulin, which will assist bring down your blood sugar level and minimize the chance of significant cardiovascular events like strokes and heart attacks that you are at risk for. In the treatment of diabetes, it is sometimes used in combination with metformin.

Tablets of the brand-name medication Rybelsus contain the same medicinal component as is found in liquid form in Ozempic.

Ozempic active ingredients

Ozempic contains semaglutide as its primary working component. It is considered to be an agonist at the GLP-1 receptor agonist. By selectively attaching to and triggering the GLP-1 receptor, semaglutide is able to decrease blood sugar levels. This is accomplished by a process that involves the stimulation of insulin production and the reduction of glucagon secretion.

Semaglutide, in contrast to many other medications for T2 diabetes, is not an insulin preparation. It is a naturally occurring hormone that has a variety of effects on the human body. After a meal, taking semaglutide may assist you in maintaining a healthier blood sugar level by stimulating your pancreas to generate more insulin. Additionally, it seems to promote the proliferation of cells in the pancreas that are responsible for insulin production (beta-cells).

The subcutaneous (subcutaneous) injection of semaglutide is administered at a frequency of once every seven days, on average. The thigh, the belly, or the upper arm may be used as the injection site. Your current health status and how well you are responding to therapy will both play a role in determining the dosage you are given. Only take an extra dosage of Ozempic if there is less than three days before your next scheduled dose and you have missed your weekly dose of the medication. Both ambient temperature and the refrigerator are suitable storage environments for the Ozempic injection.

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For the treatment of diabetes type 2

What are the benefits of Ozempic? 

The fact that Ozempic has to be administered just once a week, relieving the user of the burden of doing so on a daily basis, is only one of the advantages offered by this product.

Even though it isn’t traditionally thought of as a weight reduction tool, Ozempic may help maintain blood sugar levels at a healthy level. This, in turn, can make it easier to shed unwanted pounds. As a consequence of delayed stomach emptying, taking Ozempic lessens feelings of hunger. This, in turn, leads to less food being consumed, which ultimately leads to a reduction in overall body mass.

Side effects of Ozempic

The most prevalent adverse effects of Ozempic include:

●    Vomiting 

●    Nausea 

●    Abdominal pain

●    Diarrhea

●    Constipation

In very rare cases, Ozempic has been known to induce more significant adverse effects, including the following:

●    An increased likelihood of developing thyroid cancers, especially malignant ones

●    Problems with the kidneys, including complete kidney failure 

●    Rashes, itching, swelling, and difficulty breathing are some of the symptoms that may be brought on by severe adverse responses to the medicine

●    Pancreatic inflammation that you are experiencing (pancreatitis)

●    Alterations to your visual perception

●    Extremely low blood sugar levels (hypoglycemia)

Ozempic warnings & precautions

You should not take Ozempic if you have any of the following conditions: Are allergic to the active component semaglutide or any of the components in Ozempic .

●    Either yourself or via a member of your family have medullary thyroid carcinoma, a kind of thyroid cancer,

●    have Multiple endocrine neoplasia syndrome type 2 is a disorder that affects the glands of the endocrine system (MEN 

●    Have Pancreatitis.

●    Have diabetes type 1 as Ozempic is used for only type 2 form of diabetes 

●    Are less than 18 years of age

Before starting to use Ozempic, you should discuss the following with your physician:

●    If you have had any issues with either your kidneys or your pancreas

●    Are pregnant or have the intention of becoming pregnant in the near future

●    If you have diabetic retinopathy

●    If you are currently nursing or do you have plans to start breastfeeding


0.5 milligrams once every week 

1 milligrams once per week

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The question now is, what distinguishes Saxenda and Ozempic from one another? The sole noticeable difference between Saxenda and Ozempic is that the former, also known as liraglutide, is administered through injection once daily, whereas the latter, also known as Semaglutide, is administered via injection once every seven days. In addition to this, Saxenda is approved for use as an injectable weight reduction aid, whilst Ozempic is currently considered off-label.

Other than that, they both are quite comparable to one another and function in the same manner, attaching to receptors to suppress the appetite and, as a direct consequence, causing weight loss.

Disclaimer: The above is a sponsored post, the views expressed are those of the sponsor/author and do not represent the stand and views of Outlook Editorial.